Associate Professor Nathan Pavlos is Head of the Bone Biology and Disease Laboratory within the School of Biomedical Sciences at the University of Western Australia (UWA). He completed his Ph.D. at UWA in 2005 and undertook postdoctoral training between 2007-2010 at the Max-Planck-Institute for Biophysical Chemistry, Germany (Reinhard Jahn Laboratory) as a National Health & Medical Research Council CJ Martin (Biomedical) Overseas Research Fellow where he worked on the molecular regulation of synaptic vesicle exo-endocytosis in neurons. In 2010, he returned to UWA to start up his independent research laboratory where his current research program focuses on the cellular and molecular pathogenesis of bone diseases.  In particular, his team is interested in understanding the molecular machinery regulating membrane trafficking and transport in osteoclasts, giant bone-degrading cells, which underpin bone-wasting diseases such as osteoporosis and tumor-mediated bone loss. For this, his team uses genetically altered mice as a model organism together with innovative microscopy-based platforms to gain insights into the molecular mechanisms regulating these enigmatic bone-digesting polykaryons that may be exploited as new therapeutic targets for the treatment of bone-wasting diseases. Dr. Pavlos is a Fellow of the American Society for Bone and Mineral Research (Class of 2020), Treasurer for the Australian and New Zealand Bone and Mineral Research Society, and Secretary for the Australian and New Zealand Society for Cell and Developmental Biology.

For a preview of upcoming seminars on our program see the 2020 Oral and Craniofacial Sciences Seminar Schedule.