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UMKC Center for Research on Interfacial Structure and Properties (UMKC-CRISP)
Department of Oral Biology
Facilities
Design:
The UMKC-CRISP features three core groups of distinct yet interconnected cores. Thus, knowledge will flow freely from basic science discoveries to clinical applications and back again, creating a cycle of progress directly benefiting patients.
JASCO NRS-2000 micro-Raman spectrometer equipped with 2 sources of laser excitation, i.e., Argon: 514.5nm and Diode: 785nm. This instrumentation provides molecular structural information on a variety of samples including biological tissues, synthetic materials and tissue/material interfaces at 1 micrometer spatial resolution. Raman microspectroscopy is an exceptional tool for investigating the chemistry of material/tissue interfaces because it does not rely on homogenization, extraction, or dilution, but rather each structure is analyzed in situ. |
Perkin Elmer Spectrum Spotlight FTIR chemical imaging system and Perkin Elmer Spectrum One FTIR spectrometer provides information about molecular composition from a wide range of synthetic materials and biologic tissues. An IR image comprising hundreds or thousands of spectra is generated in real time. Each pixel represents an individual spectrum and the color intensity shows potential areas of difference. |
The high frequency scanning acoustic microscope (KSI 2000) comes with a set of 4 high precision lenses 200, 400 and 1000 MHz and the 1.3-2.0 GHz. The nominal lateral resolution with the 2 GHz lens is of the order of 500 nm. Both the high and low frequency scanning acoustic microscopes are mounted on vibration-free tables. |
The low frequency scanning acoustic microscope (Kraemer Scientific Instruments, KSI WINSAM) comes with a set of 4 high precision acoustic lenses: 10, 30, 50 and 100 MHz. This instrumentation provides acoustic property measurement at 15 micrometers resolution. |
This Research Center known as the University of Missouri-Kansas City Center for Research on Interfacial Structure & Properties (UMKC-CRISP) provides bioengineering researchers with state-of-the-art instrumentation for structure/property characterization of synthetic materials, biological tissues and the material/tissue interface. The facilities within the center provide scientists the opportunity to complete chemical, morphologic and mechanical analyses on materials and tissues. These analyses are mandatory for a comprehensive understanding; they provide the foundation for the models that will be used to design materials for the 21st century. Although some or all of the instrumentation that is available in this research center may exist at other institutions, the equipment is usually isolated in separate laboratories and to our knowledge, has not been utilized to perform the type of integrated research program that is the focus of UMKC-CRISP. The resources available within UMKC-CRISP provide investigators the opportunity to explore the spectrum of opportunities represented by the integration of biology and engineering.
 Major instrumentation available in the UMKC-CRISP includes field emission environmental scanning and transmission electron microscopes, conventional mechanical testing equipment, JASCO NRS-2000 micro-Raman spectrophotometer, Perkin Elmer FTIR Spotlight Chemical Imaging System, Kraemer Scientific Instruments (KSI) high and low frequency scanning acoustic microscopes, TA Instruments Differential Scanning Calorimetry, Zeiss brightfield, phase and fluorescent microscope coupled to image analysis system running Optimas software.
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