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Dr. Andrew Keightley is the Director of the Biological Mass Spectrometry and Proteomics Facility, and Research Associate Professor in the School of Biological Sciences at the University of Missouri-Kansas City. He received a Ph.D. in Biochemistry from the University of New Mexico-Albuquerque while completing an Associated Western Universities Laboratory Graduate Fellowship as a Research Associate at Los Alamos National Laboratories (1989-1992), studying the electron transport chain and respiration in prokaryotes. He subsequently applied his skills at the Pediatric Metabolic Laboratory at Oregon Health Sciences University, where he identified Mitochondrial DNA lesions associated with electron transport chain defects causing mitochondrial myopathies in human patients. Subsequently, Dr. Keightley focused his efforts on Biological Mass Spectrometry at the Cleveland Clinic. Dr. Keightley joined UMKC faculty in 2003, and has been building the Proteomic capabilities of the facility to include sub-femtomolar level protein identification, post-translational modification (PTM) discovery, and total proteome differential expression analysis.
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