Oral and Craniofacial Sciences Faculty

Mark Johnson, Ph.D.





















Recent Publications (More articles at PubMed)

Lara-Castillo, N. and Johnson, M.L.: “LRP receptor family member associate bone disease”. Rev Endocr Metab Disord epub ahead of print, 2015.

Lara-Castillo, N., Kim-Weroha, N.A, Kamel, M.A., Javaheri, B., Ellies, D., Krumlauf, R. and Johnson, M.L.: “In vivo Mechanical Loading Rapidly Activates β–catenin Signlaing in Osteocytes through a Prostaglandin Mediated Mechanism” Bone 76:58-66, 2015.

Johnson, M.L.: “Unlocking the Sost Gene” J Bone Mineral Research 30:397-399, 2015.

Xu, H., Gu, S., Riquelme, M.A., Burra, s., Callaway, D., Cheng, H., Guda, T., Schmitz, J., Fajardo, R., Werner, S.L., Zhao, H., Shang, P., Johnson, M.L., Bonewald, L.F. and Jiang, J.X.: “Connexin 43 Channels are Essential for Normal Bone Structure and Osteocyte Viability”. J Bone Mineral Research 30:436-448, 2015.

Thiagarajan, G., Lu, Y., Dallas, M. and Johnson, M.L.: “Experimental and Finite Element Analysis of Dynamic Loading of the Mouse Forearm” Journal of Orthopedic Research 32:1580-1588, 2014.

Kitase, Y., Lee, S., Gluhak-Heinrich, J., Johnson, M.L., Harris, S.E. and Bonewald, L.F.” CCL7 isa Protective Factor Secreted by Mechanically Loaded Osteocytes”. J Dent Res 93:1108-1115, 2014.

Srivastava, T., Alon, U., Cudmore, P., Tarakji, B., Kats, A., Garola, R., McCarthy, E., Sharma, R., Johnson, M., Bonewald, L., El-Meanawy, A., Savin, V. and Sharma, M.: Cyclooxygenase-2, Prostaglandin E2 and Prostanoid receptor EP2 in Fluid Flow Shear Stress Mediated Injury in Solitary Kidney”. Am J Physiology – Renal Phys. 307:F1323-F1333, 2014.

Mo, C.L., Romero-Suarez, S., Bonewald, L.F., Johnson, M.L. and Brotto, M.: “Evidence for Biochemical and Functional Communication from the MLO-Y4 Osteocyte-like Cell to the C2C12 Muscle Cells.” Cell Cycle in press.

Javaheri, B., Stern, A., Lara, N., Dallas, M., Zhao, H, Bonewald, L.F. and Johnson, M.L.: “β-catenin Haploinsufficiency in Osteocytes Abolishes the Osteogenic Effect of Mechanical Loading In Vivo.” J Bone Mineral Research 29:705-715, 2014.

Jahn, K., Lara-Castillo, N., Brotto, L., Mo, C.L., Johnson, M.L., Brotto, M. and Bonewald, L.F.: “Skeletal Muscle Secreted Factors Prevent Glucocorticoid-Induced Osteocyte Apoptosis through Activation of β-Catenin”. European Cells and Materials 24:197-210, 2012.

Lu, Y., Thiagarajan, G., Nicolella, D.P., and Johnson, M.L. : “Load/Strain Distribution between Ulna and Radius in the Mouse Forearm Compression Loading Model”. Med Engin Phys 34:350-356, 2012. PMID 21903442.

Xiao, Z., Dallas, M., Qiu, N., Nicolella, D., Cao, L., Johnson, M., Bonewald, L. and Quarles, L.D.: “Conditional Deletion of Pkd1 in Osteocyte Disrupts Skeletal Mechanosensing in Mice.” FASEB J 25:2418-32, 2011. PMCID: PMC3219213.

Kamel, M.A., Picconi, J.L., Lara, N. and Johnson, M.L.: “Activation of β–catenin Signaling in MLO-Y4 Osteocytic Cells versus 2T3 Osteoblastic Cells by Fluid Flow Shear Stress and PGE2: Implications for the Study of Mechanosensation in Bone”. Bone 47:872-881, 2010. PMCID: PMC2952691

Kitase, Y., Barragan, L., Qing, H., Kondoh, S., Jiang, J.X., Johnson, M.L., and Bonewald, L.F.(2010). “Mechanical Induction of PGE2 In Osteocytes Blocks Glucocorticoid Induced Apoptosis through both the β–Catenin and PKA Pathways”. J Bone Mineral Res, 25:2381-2392, 2010.

Srivastava, T., McCarthy, E.T., Sharma, R., Cudmore, P.A., Sharma, M., Johnson, M.L. and Bonewald, L.F.: “Prostaglandin E2 is Crucial in the Podocytes Response to Fluid Flow Shear Stress” J Cell Commun Signlaing. 4:79-90, 2010. PMID: 20531983

Yao, W., Cheng, Z., Shahnazari, M., Dai, W., Johnson, M.L., and Lane, N.E.: “Overexpression of Secreted Frizzled-Related Protein 1 Inhibits Bone Formation and Attenuates Parathyroid Hormone Bone Anabolic Effects” J Bone Miner Res 25: 190-199, 2010. (epub July 13, 2009) DOI:10.1359/jbmr.090719. PMID 19594295

Bonewald, L.F. and Johnson, M.L.: “Osteocytes, Mechanosensing and Wnt Signaling” Bone 42:606-615, 2008.

Little RD, Carulli J, Del Mastro RG, Dupuis J, Osborne M, …Johnson ML. A point mutation in LRP5 results in autosomal dominant high bone mass trait, Am J Hum Genet 70:11-19, 2002.

Mark Johnson, Ph.D. Professor and Department Chair

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