Oral and Craniofacial Sciences Faculty

Mark Johnson, Ph.D.





















Recent Publications (More articles at PubMed)

Kitase, Y., Barragan, L., Qing, H., Kondoh, S., Jiang, J.X., Johnson, M.L., and Bonewald, L.F.(2010). “Mechanical Induction of PGE2 In Osteocytes Blocks Glucocorticoid Induced Apoptosis through both the β–Catenin and PKA Pathways”. J Bone Mineral Res, 25:2381-2392, 2010.

Kamel, M.A., Picconi, J.L., Lara, N. and Johnson, M.L. (2010): “Activation of β–catenin Signaling in MLO-Y4 Osteocytic Cells versus 2T3 Osteoblastic Cells by Fluid Flow Shear Stress and PGE2: Implications for the Study of Mechanosensation in Bone”. Bone 47:872-881. PMCID: PMC2952691

Srivastava, T., McCarthy, E.T., Sharma, R., Cudmore, P.A., Sharma, M., Johnson, M.L. and Bonewald, L.F.(2010). “Prostaglandin E2 is Crucial in the Podocytes Response to Fluid Flow Shear Stress” J Cell Commun Signlaing. J Cell Commun Signaling 4:79-90, 2010. PMCID: PMC2876242

Yao, W., Cheng, Z., Shahnazari, M., Dai, W., Johnson, M.L., and Lane, N.E.: “Overexpression of Secreted Frizzled-Related Protein 1 Inhibits Bone Formation and Attenuates Parathyroid Hormone Bone Anabolic Effects” J Bone Miner Res 25: 190-199, 2010. (epub July 13, 2009) DOI:10.1359/jbmr.090719

Johnson, M.L., Lara, N. and Kamel, M.A.: “How Genomics has Informed Our Understanding of the Pathophysiology of Osteoporosis.” Genomic Medicine accepted, 2009.

Barragan-Adjemian, C., Lausten, L., Ang, D.B., Johnson, M., Katz, J. and Bonewald, L.F.: “Bisphosphonate-Related Osteonecrosis of the jaw: Model and Diagnosis with Cone Beam Computerized Tomography” Cells Tissues Organs 189:284-288, 2008.

Johnson, M.L. Wnt Signaling and Bone. In: Principles of Bone Biology, 3rd edition. pp. 121-137. Elsevier Press, Burlington, MA. Ed. John Bilezikian, 2008.

Bonewald, L.F. and Johnson, M.L.: “Osteocytes, Mechanosensing and Wnt Signaling” Bone 42:606-615, 2008.

Johnson, M.L. and Recker, R.R. “Wnt Signaling in Bone” In Osteoporosis, 3rd Edition, pp. 467-490, 2007. Elsevier Press, Burlington, MA. Ed. Marcus, Robert, 2007.

Johnson, M.L. and Kamel M.A.: “The Wnt Signaling Pathway and Bone Metabolism”. Current Opinion in Rheumatology, 19:376-382, 2007.

Johnson, M.L. : LRP5: Structural and Molecular Aspects. Clinical Reviews in Bone and Mineral Metablosim. 4:97-106, 2006.

Johnson, M.L. and Rajamannan, N.: “Diseases of Wnt Signaling”. Reviews in Endocrine and Metabolic Disorders. 7:41-49, 2006.

Robinson, J.A., Chatterjee-Kishore, M., Yaworsky, P.J., Cullen, D.M., Zhao, M., Li, C., Kharode, Y., Sauter, L., Babij, P., Brown, E.L., Akhter, M.P., Johnson, M.L., Recker, R.R., Komm, B.S. and Bex, F.J.: “Wnt/b-catenin Signaling is a Normal Physiological Response to Mechanical Loading in Bone”. J. Biol. Chem. 281:31720-317208, 2006.

Johnson, M.L. and Summerfield, D. T. : Parameters of LRP5 from a Structural and Molecular Perspective. Critical Reviews in Eukaryotic Gene Expression 15(3):229-242, 2005.

Johnson, M.L. Harnish, K., Nusse, R. and Van Hul, W. : LRP5 and Wnt Signaling: A Union Made for Bone. J. Bone Miner. Res. 19:1749-1757, 2004.

Johnson, M.L.: The high bone mass family – the role of Lrp5/Wnt signaling in the regulation of bone mass. J. Musculoskel. Neuron. Interact. 4:135-138, 2004.

Akhter, M.P., Wells, D.J., Short, S.J., Cullen, D.M., Johnson, M.L., Haynatzki, G., Babij, P., Allen, K.M., Yaworsky, P.J., Bex, F. and Recker, R.R.: “Bone Biomechanical Properties in Lrp5 Mutant Mice”. Bone 35:162-169, 2004.

Little RD, Recker RR, Johnson ML. High Bone Density Due to a Mutation in LDL-Receptor-Related Protein 5. Letter to the Editor, New Engl. J. Med 347:943, 2002.

Johnson ML, Picconi JL, Recker RR. The Gene for High Bone Mass, The Endocrinologist 12:445-53, 2002.

Little RD, Carulli J, Del Mastro RG, Dupuis J, Osborne M, …Johnson ML. A point mutation in LRP5 results in autosomal dominant high bone mass trait, Am J Hum Genet 70:11-19, 2002.

Mark Johnson, Ph.D. Professor and Department Chair

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